Sedge head to second-placed Barton Town Old Boys in the Toolstation Northern Counties East League Premier Division.
The Humberside outfit are just above Brighouse, who are not in action this weekend.
Barton are six points behind leaders Tadcaster Albion but have four games in hand, although Brighouse are breathing down their necks after three straight victories.
Sedge have had a poor season and are averaging just a point a game, and they also slipped down one place to 19th in midweek, even though they didn’t play.
However, they have scored eight goals in their last two games and have the capabilities to spring a shock result.
Thackley will also be looking for a win to make the most of Brighouse’s blank weekend.
The Dennyboys are at mid-table Long Eaton United, who could have gone joint ninth in midweek but were held to a home draw by mid-table rivals Bridlington Town.
Fifth-placed Thackley are in search of the win that would see them close the gap on Brighouse, who are third, and also take them through the 60-point barrier.
Eccleshill United manager Lee Duxbury insists his side is capable of mounting a late promotion push in Division One, and they could make a big statement this weekend.
The Eagles host Pontefract Collieries, who are three places higher but are only two points better off and have played a game more.
Ponte are fourth but would be overhauled by the Eagles if Duxbury can mastermind another win.
They will be brimming with confidence after their midweek third-round League Cup tie victory over Tadcaster.
Half a dozen postponements in recent weeks mean Silsden have played just once since Boxing Day but they are in line for a home game on Saturday in the North West Counties League Premier Division.
The Cobbydalers last played at home on December 14 and it was also their last win as they were defeated the following Saturday at AFC Liverpool, who coincidentally are the visitors to the Angel Telecom Stadium this weekend.
Silsden are just four points above the drop zone but they have nine games in hand on basement outfit Wigan Robin Park and four games in hand on third-from-bottom Alsager Town.
Their Merseyside visitors are a healthy seventh, just 12 points off the summit with two games in hand.
However, their title hopes are remote as four of the six clubs above them have games in hand over them.