The list, released today, combines data and statistics such as crime rates, house prices and school performance.
Skipton is ranked as one of the top four places to live in Britain.
The places were selected for offering the best quality of life to the widest number of people, and combining desirable features such as a positive community spirit, good local shops and services and attractive outdoor spaces.
Across Yorkshire and the North-East, a total of 15 places made the list. They included Barnard Castle, in County Durham, Beverley, in East Yorkshire, Chapel Allerton, Leeds, Morpeth, Northumberland, the Quayside, in Newcastle, and Ripponden, near Halifax.
North Yorkshire figures strongly, with locations including Richmond, York, Easingwold, Harrogate, Helmsley, and Masham.