The main road between Keighley and Hebden Bridge has been closed following a crash in heavy fog involving two cars.
Two people had to be cut out of a Subaru Impreza after a collision with a Vauxhall on the A6033.
Emergency services, including fire crews from Haworth and Todmorden, were called to a bend on the road between Oxenhope and Hebden Bridge at 1.13pm.
The driver of the Subaru was complaining of neck pains, and firefighers cut the roof off the vehicle to get him out safely. He and a passenger were taken by ambulance to Huddersfield Royal Infirmary.
As of 2.30pm the road was still closed.