The main road between Keighley and Hebden Bridge has been closed following a crash in heavy fog involving two cars.
Two people had to be cut out of a Subaru Impreza after a collision with a Vauxhall on the A6033.
The driver of the Subaru was complaining of neck pains, and firefighers cut the roof off the vehicle to get him out safely. He and a passenger were taken by ambulance to Huddersfield Royal Infirmary.
As of 2.30pm the road was still closed.